I-High Purity 540737-29-9 Tofacitinib citrate ye-JAK Pathway Inhibitor

Incazelo emfushane:

Ubumsulwa:≧99.0%

Izinga Lekhwalithi:I-Enterprise Standard noma njengoba kudingeka

Amandla:35Kgs/Inyanga

Impilo Yeshelufu:Iminyaka Emithathu

Isicelo:Yelapha i-rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis kanye ne-ulcerative colitis

Inzuzo Yeqembu:Ithimba labadayisi abanolwazi lokuthekelisa elinokuqeqeshwa kochwepheshe efektri

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Imininingwane Yomkhiqizo

FAQ

Omaka bomkhiqizo

Umkhiqizoigama	I-Tofacitinib Citrate
Omqondofana	(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3 - propanetricarboxylate;I-CP 690500-10;I-CP 690550-10;(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate
Inombolo ye-CAS.	540737-29-9
Ukubukeka	Impushana emhlophe iye emhlophe
I-Molecular Formula	C₁₆H₂₀N₆OC₆H₈O₇
Isisindo samangqamuzana	504.50
Isicelo	Ibanga lezemithi noma inhloso yocwaningo
Ukupakisha	Njengesicelo sakho
Isitoreji	Londoloza ezitsheni eziqinile, ezimelana nokukhanya endaweni epholile

I-Tofacitinib Citrate (CAS #540737-29-9)
IZINTO	AMAZINGA	IMIPHUMELA
Ukubukeka	Impushana emhlophe iye emhlophe	Impushana emhlophe
Ukuhlonza	I-HPLC;I-IR;HNMR	Iyahambisana
Ukuncibilika	I-Soluble ku-DMSO ngo-100mg/ml, ayincibiliki kahle kakhulu ku-ethanol, incibilika kancane emanzini njll.	Iyahambisana
Ukulahlekelwa Ekumisweni	≤0.5%	0.12%
Izinsalela ekushiseni	≤0.1%	0.05%
Izinsimbi ezinzima	≤10ppm	Iyahambisana
Izinto Ezihlobene	I-Diasteomer (RS+SR) ≤0.1% Ukungcola Okukodwa ≤0.15% Ukungcola okuphelele ≤1.0%	0.05% 0.14% 0.18%
I-Enantiomorphism Isomers	≤0.2%	Iyahambisana
Izincibilikisi Ezisele	I-Ethanol ≤5000ppm I-Methanol ≤3000ppm I-Toluene ≤890ppm	Iyahambisana
Okuqukethwe kwe-Citrate	36.2%~40%	37.8%
Ubumsulwa	≥99.0%	99.38%
Isivivinyo	60.68%~63.16% we-Tofacitinib INN 98%~102% we-Tofacitinib Citrate INN	62.04% 99.12%
Isiphetho:Iyavumelana

Ulwazi Lwenkampani

√ Isipiliyoni esigcwele se-Management layer kubalandeli befektri nabanekhono;
√ Ikhwalithi ihlale iwukucatshangelwa kwethu okuphezulu, uhlelo oluqinile lwe-QC;
√ Ithimba leminyaka engu-11 elinesipiliyoni sokuthumela ngaphandle;
√ Ilebhu ye-R&D ezimele;
√ Izinkundla zokucobelelana ngolwazi ezimbili ze-GMP zesikhathi eside ezisayiniwe;
√ Izinsiza ezicebile zamafekthri amaningi angasebenzi wephrojekthi eyenziwe ngokwezifiso;
√ Ithimba elisebenzayo elisebenza kahle elinendlela engaguquki.
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